Get ready for the next level in amino acid supplements – AminoREV!
Amino acids are the single most critical nutrient for muscle growth and recovery. AminoREV features a clinically-validated combination of Essential Amino Acids (EAA) and Branched Chain Amino Acids in the optimal Amino9™ ratio to take muscle anabolism to the max!
With BCAA and EAA working in unison with the MTOR-Activating Anabolic Recovery Matrix and Revolutionary Cellular Recovery & Hydration Matrix, it can be said with absolute confidence… AminoREV is the best amino acid supplement out!
- Amino9™ is a unique and powerful blend of EAA that may be better than protein for building muscle – just 1.5g of Amino9™ was found to increase anabolism as much as 40g whey protein!
- Leucine is the amino acid responsible for triggering Muscle Protein Synthesis, enhancing muscle growth and recovery.
- Cornerstone™ HICA and PureKIC® are leucine metabolites with even greater potential for reducing Muscle Protein Breakdown and increasing total muscle anabolism alongside the EAAs.
- AstraGin® maximizes amino acid absorption to ensure athletes get the absolute most out of every bit of AminoREV.
- NordicCherry™ tart cherry powder has been thoroughly demonstrated to increase recovery from exercise, decrease soreness, and improve performance.
Muscle Protein Synthesis and Muscle Protein Breakdown are two sides of the same muscle-building coin.
With AminoREV, you get both! The amino acids maximize muscle anabolism while HICA and KIC reduce muscle catabolism, creating the greatest net increase in muscle growth and recovery possible.
Going beyond aminos, the Tart Cherry Powder, CoCoganic™ Coconut Water Powder, and electrolytes in AminoREV reduce muscle soreness, promote rehydration, improve performance and stamina, and maintain cellular fluid balance to get you back to training faster and kick your game up a notch!
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Amino9 Revolutionary BCAA and EAA Complex
The essential amino acids (EAA) must be obtained in the diet to meet bodily needs and include the three branched chain amino acids (BCAA), leucine, isoleucine, and valine as well as lysine, threonine, phenylalanine, histidine, methionine, and tryptophan.
- The EAA, including the BCAA, is the most vital to all facets of exercise including recovery, fueling, muscle growth, and performance.
- The amino acid leucine is the most potent nutritional signal for increasing muscle protein synthesis (Norton, 2012).
- A recent study by Wilkinson et al. (2017) found 1.5g of EAA (with just 0.6g leucine) to maximally stimulate muscle protein synthesis – an amount no different from 40g whey protein. AminoRev contains 7g Amino9™ EAA.
MTOR Activating Anabolic Recovery Matrix
Alpha-Ketoisocaproate (KIC) is a direct metabolite of leucine. While leucine increase muscle protein synthesis, its metabolites are largely responsible for its anti-catabolic effects.
- Oxidation of leucine to KIC may be the first step to halting muscle proteolysis (muscle breakdown), first reported by Tischler, Desautels, and Goldberg (1982).
- KIC may reduce exercise-induced muscle damage, strength decrements, and muscle damage (Van Someren et al., 2005)
Cornerstone™ HICA Dihydrate
HICA (alpha-hydroxyisocaproic acid) is a metabolite of KIC, also known as leucic acid. Similar to KIC, HICA aids in the resistance of muscle damage and breakdown.
- Just 4 weeks of HICA supplementation has been found to increase lean body mass and reduce delayed-onset muscle soreness (DOMS) by tipping the scales in favor of anabolism (Mero et al., 2010).
A combination of Astragalus Membranaceus and Panax Notoginseng, AstraGin has been validated to enhance nutrient absorption.
- Increases genetic expression of nutrient transporters along the intestinal wall
- Enhances amino acid absorption by 41% and leucine absorption by 58%
MTOR Activating Anabolic Recovery Matrix
NordicCherry Part of exercise-induced muscle damage and soreness is due to pro-oxidation and oxidative damage from free radicals. Tart Cherry Powders and Juices have been observed to enhance exercise recovery by functioning as an antioxidant.
- Levers et al. (2016) demonstrated that 10 days supplementation with tart cherry powder can reduce muscle catabolism and inflammatory markers while improving endurance.
- Recovery from resistance training is sped by tart cherry consumption, as evidenced by greater recovery of muscle contractile force 2 days following a resistance training bout (Sumners et al., 2011).
CoCoganic Coconut Water & Electrolytes
Coconut water and electrolytes help accelerate recovery of essential bodily fluids to maintain proper cellular functioning and athletic performance.
- A study comparing carbs + electrolyte vs. aminos + electrolyte found greater cellular rehydration with the amino + electrolyte blend, which also contained more potassium and magnesium (Tai, et al., 2014).
- Coconut water has been suggested to be a superior rehydration beverage than both carbohydrate-electrolyte drinks and plain water by equally restoring body fluids and being easier to drink (Saat et al., 2002).
Vitamin D may be the most insufficiently consumed micronutrient in the world. Vitamin D is associated with a plethora of benefits including greater testosterone levels, bone integrity, immunity, and reduced risk of cancer.
- Daily supplementation with 83 micrograms of vitamin D has been observed to increase testosterone in men with deficient testosterone levels (Pilz et al., 2011).
- Vitamin D has increased fat-free mass while decreasing fat mass following 12 weeks of daily supplementation (Salehpour et al., 2012).
Q: How Should I Use AminoRev?
A: As a dietary supplement, mix 1 level scoop (13 grams) in 12-16 oz of water and consume at least once per day.
Use twice per day for best results. AminoRev may be consumed throughout the day as well as before, during, or after training to help increase muscle anabolism.
Q: How are Muscle Protein Synthesis, Anabolism, Muscle Protein Breakdown, and Catabolism related?
A: Muscle Protein Synthesis, or MPS, is the process by which new muscle proteins are formed, and it is an anabolic (building) process. Muscle Protein Breakdown, or MPB, is the process of breaking down (catabolizing) existing muscle proteins to their individual amino acid parts.
The body is in a constant state of both MPS and MPB, and we can tip the scales in favor of MPS with proper nutrition (protein, EAA, and BCAA) and exercise.
Q: Are There Other MuscleSport Products that Pair Well with AminoRev?
A: Yes! Your goal will determine how best to stack AminoRev.
For Mass Building, stack AminoRev with Kre4Max Pro Creatine Blend and consume between high protein meals. Preworkout, AminoRev can be stacked with Rhino BLACK Pumped for insane pumps and maximal growth stimulation.
1. Norton, L. E., Wilson, G. J., Layman, D. K., Moulton, C. J., & Garlick, P. J. (2012). Leucine content of dietary proteins is a determinant of postprandial skeletal muscle protein synthesis in adult rats. Nutrition & metabolism, 9(1), 67.
2. Wilkinson, D. J., Bukhari, S. S., Phillips, B. E., Limb, M. C., Cegielski, J., Brook, M. S., ... & Lund, J. (2017). Effects of leucine-enriched essential amino acid and whey protein bolus dosing upon skeletal muscle protein synthesis at rest and after exercise in older women. Clinical Nutrition.
3. Norton, L. E., & Layman, D. K. (2006). Leucine regulates translation initiation of protein synthesis in skeletal muscle after exercise. The Journal of nutrition, 136(2), 533S-537S.
4. Rasmussen, B. B., Tipton, K. D., Miller, S. L., Wolf, S. E., & Wolfe, R. R. (2000). An oral essential amino acid-carbohydrate supplement enhances muscle protein anabolism after resistance exercise. Journal of applied physiology, 88(2), 386-392.
5. Volpi, E., Kobayashi, H., Sheffield-Moore, M., Mittendorfer, B., & Wolfe, R. R. (2003). Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults. The American journal of clinical nutrition, 78(2), 250-258.
6. Tipton, K. D., Ferrando, A. A., Phillips, S. M., Doyle Jr, D., & Wolfe, R. R. (1999). Postexercise net protein synthesis in human muscle from orally administered amino acids. American Journal of Physiology-Endocrinology And Metabolism, 276(4), E628-E634.
7. Paddon-Jones, D., Sheffield-Moore, M., Zhang, X. J., Volpi, E., Wolf, S. E., Aarsland, A., ... & Wolfe, R. R. (2004). Amino acid ingestion improves muscle protein synthesis in the young and elderly. American Journal of Physiology-Endocrinology And Metabolism, 286(3), E321-E328.
KIC & HICA
1. Tischler, M. E., Desautels, M., & Goldberg, A. L. (1982). Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle?. Journal of Biological Chemistry, 257(4), 1613-1621.
2. Van Someren, K. A., Edwards, A. J., & Howatson, G. (2005). Supplementation with β-hydroxy-β-methylbutyrate (HMB) and α-ketoisocaproic acid (KIC) reduces signs and symptoms of exercise-induced muscle damage in man. International journal of sport nutrition and exercise metabolism, 15(4), 413-424.
3. Mero, A. A., Ojala, T., Hulmi, J. J., Puurtinen, R., Karila, T. A., & Seppälä, T. (2010). Effects of alfa-hydroxy-isocaproic acid on body composition, DOMS and performance in athletes. Journal of the International Society of Sports Nutrition, 7(1), 1.
4. Hutson, S. M., Zapalowski, C., Cree, T. C., & Harper, A. E. (1980). Regulation of leucine and alpha-ketoisocaproic acid metabolism in skeletal muscle. Effects of starvation and insulin. Journal of Biological Chemistry, 255(6), 2418-2426.
5. Walser, M., Lund, P., Ruderman, N. B., & Coulter, A. W. (1973). Synthesis of essential amino acids from their α-keto analogues by perfused rat liver and muscle. The Journal of clinical investigation, 52(11), 2865-2877.
Tart Cherry Powder
1. Sumners, D. P., Dyer, A., Fox, P., Mileva, K. N., & Bowtell, J. (2011). Montmorency cherry juice reduces muscle damage caused by intensive strength exercise.
2. Levers, K., Dalton, R., Galvan, E., O’Connor, A., Goodenough, C., Simbo, S., ... & Crouse, S. (2016). Effects of powdered Montmorency tart cherry supplementation on acute endurance exercise performance in aerobically trained individuals. Journal of the International Society of Sports Nutrition, 13(1), 22.
3. Levers, K., Dalton, R., Galvan, E., Goodenough, C., O’Connor, A., Simbo, S., ... & Riechman, S. (2015). Effects of powdered Montmorency tart cherry supplementation on an acute bout of intense lower body strength exercise in resistance trained males. Journal of the International Society of Sports Nutrition, 12(1), 41.
4. Goodenough, C., Levers, K., Dalton, R., Galvan, E., O’Connor, A., Simbo, S., ... & Jung, Y. P. (2014). Powdered tart cherry supplementation mitigates the post-exercise immune response with reduction in total antioxidant status and serum triglyceride levels following an acute bout of intense endurance exercise. Journal of the International Society of Sports Nutrition, 11(1), P34.
5. Bell, P. G., McHugh, M. P., Stevenson, E., & Howatson, G. (2014). The role of cherries in exercise and health. Scandinavian journal of medicine & science in sports, 24(3), 477-490.
Coconut Water & Electrolytes
1. Tai, C. Y., Joy, J. M., Falcone, P. H., Carson, L. R., Mosman, M. M., Straight, J. L., ... & Moon, J. R. (2014). An amino acid-electrolyte beverage may increase cellular rehydration relative to carbohydrate-electrolyte and flavored water beverages. Nutrition journal, 13(1), 47.
2. Saat, M., Singh, R., Sirisinghe, R. G., & Nawawi, M. (2002). Rehydration after exercise with fresh young coconut water, carbohydrate-electrolyte beverage and plain water. Journal of physiological anthropology and applied human science, 21(2), 93-104.
3. Kalman, D. S., Feldman, S., Krieger, D. R., & Bloomer, R. J. (2012). Comparison of coconut water and a carbohydrate-electrolyte sport drink on measures of hydration and physical performance in exercise-trained men. Journal of the International Society of Sports Nutrition, 9(1), 1.
4. Maughan, R. J., Owen, J. H., Shirreffs, S. M., & Leiper, J. B. (1994). Post-exercise rehydration in man: effects of electrolyte addition to ingested fluids. European journal of applied physiology and occupational physiology, 69(3), 209-215.
5. Stand, A. P. (2009). Exercise and fluid replacement. Medicine and science in sports and exercise, 39(2), 377-390.
1. Salehpour, A., Hosseinpanah, F., Shidfar, F., Vafa, M., Razaghi, M., Dehghani, S., ... & Gohari, M. (2012). A 12-week double-blind randomized clinical trial of vitamin D 3 supplementation on body fat mass in healthy overweight and obese women. Nutrition journal, 11(1), 78.
2. Pilz, S., Frisch, S., Koertke, H., Kuhn, J., Dreier, J., Obermayer-Pietsch, B., ... & Zittermann, A. (2011). Effect of vitamin D supplementation on testosterone levels in men. Hormone and Metabolic Research, 43(3), 223.
3. Nazarian, S., Peter, J. V. S., Boston, R. C., Jones, S. A., & Mariash, C. N. (2011). Vitamin D3 supplementation improves insulin sensitivity in subjects with impaired fasting glucose. Translational research, 158(5), 276-281.
4. Pludowski, P., Holick, M. F., Pilz, S., Wagner, C. L., Hollis, B. W., Grant, W. B., ... & Soni, M. (2013). Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality—a review of recent evidence. Autoimmunity reviews, 12(10), 976-989.
5. Buckley, L. M., Leib, E. S., Cartularo, K. S., Vacek, P. M., & Cooper, S. M. (1996). Calcium and vitamin D3 supplementation prevents bone loss in the spine secondary to low-dose corticosteroids in patients with rheumatoid arthritis: a randomized, double-blind, placebo-controlled trial. Annals of internal medicine, 125(12), 961-968.
6. Wehr, E., Pilz, S., Boehm, B. O., März, W., & Obermayer‐Pietsch, B. (2010). Association of vitamin D status with serum androgen levels in men. Clinical Endocrinology, 73(2), 243-248.
7. Lappe, J. M., Travers-Gustafson, D., Davies, K. M., Recker, R. R., & Heaney, R. P. (2007). Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial. The American journal of clinical nutrition, 85(6), 1586-1591.
8. Autier, P., & Gandini, S. (2007). Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials. Archives of internal medicine, 167(16), 1730-1737.
1. AstraGin Product Dossier, Sections 6.4 – 6.17 2. Lu L., et al. Astragalus polysaccharides decrease muscle wasting through Akt/mTOR, ubiquitin proteasome and autophagy signaling in 5/6 nephrectomized rats. J Ethnopharmacol. 2016;186:125-135
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