Rhino For HER

$49.99

PRE-TRAINING AMPLIFIER FOR HER

  • Pre-workout specifically dosed for women*
  • Intense energy without the crash*
  • Boosts focus, mood, & concentration abilities*
  • Increases endurance and power output*
  • Lessens fatigue by enhancing blood flow to working muscles*
  • Delicious flavors

 

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Description

Pre-workouts are a great solution to help you find the energy and motivation to push through an intense training session. But have you ever wondered why a woman would take the same pre-workout as a man when there is a clear disparity in bodyweight and overall goals? When a typical pre-workout says “1 scoop” as a serving size – it is typically not the correct dose for both a man AND a woman. This is the concept behind RHINO for HER…a pre-workout created just for women that takes the guesswork out of whether you are getting the correct doses of key ingredients to enhance performance while avoiding the “cracked out” feeling and ill effects often associated with regular pre-workout powders. Take a look at the label and you will find RHINO for HER contains:

Caffeine Matrix– All the fat-burning, attention-enhancing effects of caffeine without the hard crash or upset stomach!
Choline Complex – Choline is the precursor to acetylcholine, a neurotransmitter that can boost focus, mood, and concentration abilities.
Nitrosigine– The world’s most effective form of arginine that improves blood flow up to 3 hours.
Tauric Acid – Improves time to exhaustion, VO2 Max, and maximal workload.

RHINO for HER will help supply all the energy, focus, and pump needed to smash your workouts from start to finish – at the same time you’ll know it’s made JUST FOR HER. You don’t use your man’s deodorant or other personal care items, so stop using his pre-workout formula and start using RHINO for HER, a pre-workout created for women just like you!

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Ingredient Profile

RHINO MODE ENERGY COMPLEX

Choline Complex (CDP Choline/Choline Bitartrate):

Choline is an essential nutrient for brain health and synaptic plasticity.

  • Choline improves structural integrity, signaling capacity and the fluidity of neural membranes. It’s estimated that close to 90% of the population does not get the recommended amount of choline daily.
  • It has been shown that a dose of 500mg of Choline can boost focus, mood and concentration abilities.
  • This is tantamount to pushing through your workout. Utilizing this effectively dosed compound, you will be able to focus on taking less rest or being distracted during you training. Giving your 110% will really be your 110%.
  • A study conducted by Sun et al. (1999) reported that subjects who supplemented with choline for 4 weeks improved learning performance and memory compared to a placebo group.

Methylxanthine Complex (Caffeine Anhydrous, Dicaffeine Malate, Caffeine Citrate):

This blend of caffeine helps to provide effectively dosed stimulation for your training and not keep you up all night long.

  • It is also formulated to help fight that horrible crash you might experience with stimulated laden pre-workouts.
  • Multiple studies have confirmed can improve muscular endurance and power, focus and cognitive performance, and improve energy levels. Caffeine has also been shown to have a thermogenic effect (heating/calorie burning) at rest and may increase the use of fats for fuel during exercise.
  • Doherty and Smith performed a meta-analysis of caffeine’s effects on perceived exertion and found a 5.6% decrease in RPE (rating of perceived exhertion) during exercise.  This means exercise may feel easier at higher effort levels when supplementing with caffeine.

RHINO CNS STIM COMPLEX

Hordenine:

Extracted from the roots of sprouted barley, hordenine has an adrenaline-like effect stemming from its ability to release norandrenaline.

  • This increases heart rate and blood flow.
  • The adrenaline effect is long lasting and does not fade early in your workouts. This will create a boost in athletic performance throughout your entire workout.
  • Hordenine may also increase peripheral blood flow volume and have a positive inotropic effect (increases strength of contraction) upon the heart.

Higenamine:

Higenamine Hydrochloride is a proven beta 1 and 2 adrenergic agonist; meaning that when found in a pre-workout it can help improve focus, enhance mental clarity, increase energy, and burn body fat.

  • Higenamine has also been shown to open up lung capacity by relaxing the trachea, allowing more oxygen to get into your body during training.
  • While most stimulants do the opposite of vascular relaxation and vasodilation, higenmanine has been shown to do just this. It also works synergistically with agmatine sulfate that is in RHINO for HER.

Synephrine HCL:

Best known as an alternative for ephedrine, Synephrine has several of the same benefits of ephedrine but not nearly the same side-effects.

  • Syneprhrine can reduce appetite, increase alertness, burn fat, increase metabolism and increase energy.
  • However, like ephedrine, if you take this too close to bedtime – it could create some insomnia.
  • Stohs et al. (2011) found that a single dose of synephrine given to healthy subjects in a rested state increased resting metabolic rate without any negative influence on blood pressure or cognition.

Halostachine:

Another ingredient that shares similarities with beta adrenergic receptor agonists. This means Halostachine will stimulate the beta receptors which are found on fat cells. This stimulation causes the fat to be burned as energy.

  • In an en vitro study of the pharmacodynamics and Structure Activity Relationship (SAR) of various epinephrine-like compounds, halostachine was demonstrated to be 19% as effective as epinephrine in activating beta2 receptors.

RHINO MODE NITRO COMPLEX

Inositol arginine silicate (NITROSIGINE):

Arginine (NITROSIGINE) is a precursor to nitric oxide and expands blood vessels to optimize blood flow. Silicate is contained within the walls of the arteries to help maintain their structural integrity.

  • These ingredients works in synergy to help increase the blood flow and the structural integrity of the artery walls.
  • Preclinical data has shown that Nitrosigine is superior to standard arginine… with 2x the blood flow in vasodilatation response.

Tauric Acid:

Tauric acid, has a myriad of benefits. From helping the body to metabolize fat, improving insulin sensitivity, raising testosterone levels, as an antioxidant, higher performance and quicker recovery during athletic training and increasing cardiovascular health… it goes without saying that tauric acid is a great ingredient to have in your wheelhouse

  • Zhang et al. (2004) found that individuals who supplemented with taurine for 1 week before an exhaustive exercise bout significantly improved time to exhaustion, VO2 max, and maximal workload. It also decreased exercise induced DNA damage.

Agmatine Sulfate

Agmatine Sulfate helps improve nutrient partitioning which leads to an increase in muscle glycogen (carbs stored in muscle tissues) which then leads to more water retained WITHIN the muscle. This creates a fuller look to the muscles and a greater pump while hitting the iron.

  • Agmatine Sulfate also increases NO production by working as a competitive inhibitor of the enzyme NO Synthase.
  • There are studies to suggest that the nutrient partitioning effects of agmatine sulfate are possibly due to its ability to increase the insulin response to carbohydrates. This could be further explained by the increased blood flow to the muscle that occurs with increased NO production.
  • LH and GH levels have been shown to be increased through the effects of Agmatine Sulfate and its possible effects on the hypothalamus.
  • Agmatine has also been shown to manipulate pain receptors which may allow you to train past normal pain thresholds.

Diindolylmethane (DIM):

DIM have diverse effects on estrogen metabolism. As stress of exercise goes up – hormones can be effected.

  • DIM has been shown to regulate estrogen at the receptor level to prevent it from reaching levels too high or too low.
  • DIIM also exerts numerous anti-carcinogenic (anti-cancer) effects in the body
  • A study done by Chang et al. (2011) using Indole-3-Carbinol (a precursor to DIM) noted that 5mg injections into the gut daily was able to attenuate the expected gain in body fat associated with a high fat/calorie diet.
FAQs

Q: What is the best way to take RHINO for HER?
A: Mix one scoop of RHINO for HER into 6-8 ounces of water and consume 30 minutes prior to training.

Q: What other MuscleSport products do you recommend stacking with RHINO for HER?
A: To address your pre, intra, and post workout energy, muscle building, and recovery needs we suggest stacking RHINO for HER with BCAA REVOLUTION and LEAN WHEY REVOLUTION.

Q: I see a full serving of RHINO for HER has 400mg of caffeine. Is that amount safe?
A: Generally speaking, yes. A large review by the European Food Safety Authority concluded that a daily safe dose of 400mg is safe for adults. We suggest not taking any other stimulants (like coffee) on the days you take RHINO for HER. We also recommend starting with a half scoop to assess your tolerance before moving on to a full scoop.

Q: Why is there no creatine in RHINO for HER?
A: While creatine is great for increasing power, strength, and endurance; a negative side effect (in some cases depending on the goal) is weight gain. If you want all the benefits of creatine without the weight gain stack 1/2 scoop of one of MuscleSport’s raw ingredient creatines with RHINO for HER.

Q: How is RHINO for HER different from a regular pre-workout?
A: Since men and women are different from a physiological standpoint (muscle mass, weight, metabolism, etc) when a pre-workout says “1 scoop” as a serving size – it is typically not the correct dose for both a man AND a woman. This was the concept behind RHINO for HER. To research and develop a clinically dosed product that a woman wouldn’t need to worry about guessing the correct amount of ingredient to take for maximal performance.

References

Carnosyn Beta-Alanine:
1. Hobson, R. M., Saunders, B., Ball, G., Harris, R. C., & Sale, C. (2012). Effects of β-alanine supplementation on exercise performance: a meta-analysis. Amino acids, 43(1), 25-37.
2. Stout, J. R., Cramer, J. T., Zoeller, R. F., Torok, D., Costa, P., Hoffman, J. R., … & O’kroy, J. (2007). Effects of β-alanine supplementation on the onset of neuromuscular fatigue and ventilatory threshold in women. Amino acids,32(3), 381-386.
3. Smith, A. E., Walter, A. A., Graef, J. L., Kendall, K. L., Moon, J. R., Lockwood, C. M., … & Stout, J. R. (2009). Effects of β-alanine supplementation and high-intensity interval training on endurance performance and body composition in men; a double-blind trial. Journal of the International Society of Sports Nutrition, 6(1), 1-9.
4. Baguet, A., Bourgois, J., Vanhee, L., Achten, E., & Derave, W. (2010). Important role of muscle carnosine in rowing performance. Journal of Applied Physiology, 109(4), 1096-1101.
5. Trexler, E. T., Smith-Ryan, A. E., Stout, J. R., Hoffman, J. R., Wilborn, C. D., Sale, C., … & Campbell, B. (2015). International society of sports nutrition position stand: Beta-Alanine. Journal of the International Society of Sports Nutrition, 12(1), 1-14.

Choline Complex:
1. Moreno, H., de Brugada, I., & Hall, G. (2013). Chronic dietary choline supplementation modulates attentional change in adult rats. Behavioural brain research, 243, 278-285.
2. Blusztajn, J. K., & Mellott, T. J. (2013). Neuroprotective actions of perinatal choline nutrition. Clinical Chemistry and Laboratory Medicine, 51(3), 591-599.
3. Krzysztof Blusztajn, J., & J Mellott, T. (2012). Choline nutrition programs brain development via DNA and histone methylation. Central Nervous System Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Central Nervous System Agents), 12(2), 82-94.
4. Biasi, E. (2011). The effects of dietary choline. Neuroscience bulletin, 27(5), 330-342.

MethylXanthine Complex (Caffeine Anhydrous, DiCaffeine Malate, Caffeine Citrate):
1. Goldstein, E. R., Ziegenfuss, T., Kalman, D., Kreider, R., Campbell, B., Wilborn, C., … & Wildman, R. (2010). International society of sports nutrition position stand: caffeine and performance. J Int Soc Sports Nutr, 7(1), 5.
2. Spriet, L. L. (1995). Caffeine and performance. International journal of sport nutrition, 5, S84-S84.
3. Beck, T. W., Housh, T. J., Schmidt, R. J., Johnson, G. O., Housh, D. J., Coburn, J. W., & Malek, M. H. (2006). The acute effects of a caffeine-containing supplement on strength, muscular endurance, and anaerobic capabilities. The Journal of Strength & Conditioning Research, 20(3), 506-510.
4. McLellan, T. M., Kamimori, G. H., Voss, D. M., Tate, C., & Smith, S. J. (2007). Caffeine effects on physical and cognitive performance during sustained operations. Aviation, space, and environmental medicine, 78(9), 871-877.
5. Lieberman, H. R., Tharion, W. J., Shukitt-Hale, B., Speckman, K. L., & Tulley, R. (2002). Effects of caffeine, sleep loss, and stress on cognitive performance and mood during US Navy SEAL training. Psychopharmacology, 164(3), 250-261.
6. Costill, D. L., Dalsky, G. P., & Fink, W. J. (1977). Effects of caffeine ingestion on metabolism and exercise performance. Medicine and science in sports, 10(3), 155-158.
7. Kovacs, E. M., Stegen, J. H., & Brouns, F. (1998). Effect of caffeinated drinks on substrate metabolism, caffeine excretion, and Performance. Journal of Applied physiology, 85(2), 709-715.

Hordenine:
1. Barwell, C. J., Basma, A. N., Lafi, M. A. K., & Leake, L. D. (1989). Deamination of hordenine by monoamine oxidase and its action on vasa deferentia of the rat. Journal of pharmacy and pharmacology, 41(6), 421-423.
2. Hapke, HJ, Strathmann, W. (1995). Pharmacological effects of Hordenine. Dtsch Tierarztl Wochenschr. 1995 Jun;102(6):228-32.
3. Frank, M., Weckman, T. J., Wood, T., Woods, W. E., TAI, C. L., CHANG, S. L., … & Tobin, T. (1990). Hordenine: pharmacology, pharmacokinetics and behavioural effects in the horse. Equine veterinary journal, 22(6), 437-441.

Higenamine:
1. Bai, G., Yang, Y., Shi, Q., Liu, Z., & Zhang, Q. (2008). Identification of higenamine in Radix Aconiti Lateralis Preparata as a beta2‐adrenergic receptor agonist1. Acta Pharmacologica Sinica, 29(10), 1187-1194.
2. Kam, S. C., Do, J. M., Choi, J. H., Jeon, B. T., Roh, G. S., Chang, K. C., & Hyun, J. S. (2012). The relaxation effect and mechanism of action of higenamine in the rat corpus cavernosum. International journal of impotence research, 24(2), 77-83.
3. Tsukiyama, M., Ueki, T., Yasuda, Y., Kikuchi, H., Akaishi, T., Okumura, H., & Abe, K. (2009). Beta2-adrenoceptor-mediated tracheal relaxation induced by higenamine from Nandina domestica Thunberg. Planta medica, 75(13), 1393-1399.
4. Zhou, S. J., & Du, G. Y. (2003). [Effects of higenamine on the cardio-circulatory system]. Zhongguo Zhong yao za zhi= Zhongguo zhongyao zazhi= China journal of Chinese materia medica, 28(10), 910-913.
5. Kang, Y. J., Lee, Y. S., Lee, G. W., Lee, D. H., Ryu, J. C., Yun-Choi, H. S., & Chang, K. C. (1999). Inhibition of activation of nuclear factor κB is responsible for inhibition of inducible nitric oxide synthase expression by higenamine, an active component of aconite root. Journal of Pharmacology and Experimental Therapeutics, 291(1), 314-320.
6. Pyo, M. K., Lee, D. H., Kim, D. H., Lee, J. H., Moon, J. C., Chang, K. C., & Yun-Choi, H. S. (2008). Enantioselective synthesis of (R)-(+)-and (S)-(−)-higenamine and their analogues with effects on platelet aggregation and experimental animal model of disseminated intravascular coagulation.Bioorganic & medicinal chemistry letters, 18(14), 4110-4114.

Synephrine HCL:
1. Stohs, S. J., et al. Effects of p-synephrine alone and in combination with selected bioflavonoids on resting metabolism, blood pressure, heart rate and self-reported mood changes. Int J Med Sci. 8(4):295-301, 2011.
2. Stohs, S. J., et al. A review of the human clinical studies involving Citrus aurantium (bitter orange) extract and its primary protoalkaloid p-synephrine. Int J Med Sci. 9(7):527-38, 2012.
3. Sale, C., et al. Metabolic and physiological effects of ingesting extracts of bitter orange, green tea and guarana at rest and during treadmill walking in overweight males. International Journal of Obesity 1:10, 2006.
4. Gougeon, R., et al. Increase in the thermic effect of food by adrenergic amines extracted from Citrus aurantium. Obesity Research 13(7):1187-94, 2005.
5. Zenk, J. L., et al. Effect of multi-ingredient weight-loss product on metabolic rate and body composition. Nutrition 21:179-185, 2005.
6. Preuss, H. G., et al. Citrus aurantium as a thermogenic, weight reduction replacement for ephedra: An overview. Journal of Medicine 33:1-4, 2002.
7. Stohs, S. J., et al. A review of the receptor-binding properties of p-synephrine as related to its pharmacological effects. Oxidative Medicine and Cellular Longevity, 2001.
8. Stohs, S. J., et al. The safety of Citrus aurantium (bitter orange) and its primary protoalkaloid p-synephrine. Phytotherapy Research, 2011.
9. Kaats, G.R. et al. A 60day double-blind, placebo controlled safety study involving Citrus aurantium (bitter orange) extract. Food and Chemical Toxicology 55:358-362, 2013.
10. Seifert, J. G., et al. Effect of acute administration of an herbal preparation on blood pressure and heart rate in humans. International Journal of Medical Sciences 8(3):192-197, 2011.
11. Stohs, S. J. and Preuss, H. G. Stereochemical and physiological differences between naturally occurring p-synephrine and synthetic p-synephrine. Journal of Functional Foods 4:2-5, 2012.

Halostachine:
1. Yao, X., Parnot, C., Deupi, X., Ratnala, V. R., Swaminath, G., Farrens, D., & Kobilka, B. (2006). Coupling ligand structure to specific conformational switches in the β2-adrenoceptor. Nature chemical biology, 2(8), 417-422.
2. Shannon, H. E., Cone, E. J., & Yousefnejad, D. A. V. I. D. (1982). Physiologic effects and plasma kinetics of beta-phenylethylamine and its N-methyl homolog in the dog. Journal of Pharmacology and Experimental Therapeutics, 223(1), 190-196.
3. Aasen, A. J., Culvenor, C. C. J., Finnie, E. P., Kellock, A. W., & Smith, L. W. (1969). Alkaloids as a possible cause of ryegrass staggers in grazing livestock. Crop and Pasture Science, 20(1), 71-86.
4. Liapakis, G., Chan, W. C., Papadokostaki, M., & Javitch, J. A. (2004). Synergistic contributions of the functional groups of epinephrine to its affinity and efficacy at the β2 adrenergic receptor. Molecular pharmacology, 65(5), 1181-1190.
5. Osamu, S., Masakazu, O., & Yoshinao, K. (1980). Characterization of N-methylphenylethylamine and N-methylphenylethanolamine as substrates for type A and type B monoamine oxidase. Biochemical pharmacology, 29(19), 2563-2566.

Nitrosigine:
1. Kalman, D. S., Feldman, S., Samson, A., & Krieger, D. R. (2015). A clinical evaluation to determine the safety, pharmacokinetics, and pharmacodynamics of an inositol-stabilized arginine silicate dietary supplement in healthy adult males. Clinical pharmacology: advances and applications, 7, 103.

Taurine:
1. Zhang, M., Izumi, I., Kagamimori, S., Sokejima, S., Yamagami, T., Liu, Z., & Qi, B. (2004). Role of taurine supplementation to prevent exercise-induced oxidative stress in healthy young men. Amino acids, 26(2), 203-207.
2. BOUCHAMA, A., YUSUF, A., AL-SEDAIRY, S. U. L. T. A. N., & EL-YAZIGI, A. D. N. A. N. (1993). Alteration of taurine homeostasis in acute heatstroke.Critical care medicine, 21(4), 551-554.
3. Gwacham, N., & Wagner, D. R. (2012). Acute effects of a caffeine-taurine energy drink on repeated sprint performance of American college football players. Int J Sport Nutr Exerc Metab, 22(2), 109-116.
4. Warskulat, U., Brookmann, S., Felsner, I., Brenden, H., Grether‐Beck, S., & Häussinger, D. (2008). Ultraviolet A induces transport of compatible organic osmolytes in human dermal fibroblasts. Experimental dermatology, 17(12), 1031-1036.

Agmatine Sulfate:
1. Ahn, S. K., S. Hong, et al. (2011). “Effects of agmatine on hypoxic microglia and activity of nitric oxide synthase.” Brain Res 1373: 48-54.
2. Arndt, M. A., V. Battaglia, et al. (2009). “The arginine metabolite agmatine protects mitochondrial function and confers resistance to cellular apoptosis.” Am J Physiol Cell Physiol 296(6): C1411-1419.
3. Berkels, R., D. Taubert, et al. (2004). “Agmatine signaling: odds and threads.” Cardiovasc Drug Rev 22(1): 7-16.
4. Gao, Y., B. Gumusel, et al. (1995). “Agmatine: a novel endogenous vasodilator substance.” Life Sci 57(8): PL83-86.
5. Haenisch, B., I. von Kugelgen, et al. (2008). “Regulatory mechanisms underlying agmatine homeostasis in humans.” Am J Physiol Gastrointest Liver Physiol 295(5): G1104-1110.
6. Halaris, A. and J. Plietz (2007). “Agmatine: metabolic pathway and spectrum of activity in brain.” CNS Drugs 21(11): 885-900.
7. L-arginine stimulation of glucose-induced insulin secretion through membrane depolarization and independent of nitric oxide.
8. Keynan, O., Mirovsky, Y., Dekel, S., Gilad, V. H., & Gilad, G. M. (2010). Safety and Efficacy of Dietary Agmatine Sulfate in Lumbar Disc‐associated Radiculopathy. An Open‐label, Dose‐escalating Study Followed by a Randomized, Double‐blind, Placebo‐controlled Trial. Pain Medicine, 11(3), 356-368.

Diindolylmethane:
1. Chang, H. P., Wang, M. L., Chan, M. H., Chiu, Y. S., & Chen, Y. H. (2011). Antiobesity activities of indole-3-carbinol in high-fat-diet–induced obese mice. Nutrition, 27(4), 463-470.
2. Aggarwal, B. B., & Ichikawa, H. (2005). Molecular targets and anticancer potential of indole-3-carbinol and its derivatives. Cell cycle, 4(9), 1201-1215.
3. Pappa, G., Strathmann, J., Löwinger, M., Bartsch, H., & Gerhäuser, C. (2007). Quantitative combination effects between sulforaphane and 3, 3′-diindolylmethane on proliferation of human colon cancer cells in vitro.Carcinogenesis, 28(7), 1471-1477.
4. Vivar, O. I., Saunier, E. F., Leitman, D. C., Firestone, G. L., & Bjeldanes, L. F. (2010). Selective activation of estrogen receptor-β target genes by 3, 3′-diindolylmethane. Endocrinology, 151(4), 1662-1667.
5. Lo, R., & Matthews, J. (2010). A New Class of Estrogen Receptor Beta–Selective Activators. Molecular interventions, 10(3), 133.

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Warning

While not illegal, some of the ingredients found in this product could lead to a false positive drug test and may also be banned by WADA or other professional organizations such as the NCAA. If you are a professional, college, or amateur athlete whose given sports conduct in and out of competition random drug screens is it highly recommended you check with the appropriate person before taking this product.