MuscleSport TUDCA (Tauroursodeoxycholic acid) is a water-soluble bile acid that shows great ability to treat liver cholestasis (bile acid accumulation and backup in the liver) via counteracting the toxicity of regular bile acids. These toxic bile salts can be damaging to cells by destroying the membranes and signaling for cell death. TUDCA supplements compete with this toxicity and thus indirectly protect cells from death. TUDCA is especially beneficial for those engaged in a strength training program who also take oral performance enhancement products. These products can often inhibit the production and flow of bile from the liver which can have long-term, negative consequences.
- Reduces liver and endoplasmic reticulum stress.
- Enhances insulin sensitivity.
- Helps eliminate toxins and protect against potentially harmful oral compounds.
- May offer neuroprotective effects.
TUDCA supplementation may also reduce endoplasmic reticulum stress throughout the body, not just in the liver. The endoplasmic reticulum is the organelle within cells that transports proteins out of cells. As a result, there are widespread uses of TUDCA for potentially enhancing nitrogen balance, reducing cholesterol, increase neuroprotection, and positively influence thyroid hormones in fat loss. In addition, research on daily TUDCA supplementation has found huge increases to insulin sensitivity! The 30% increase in insulin sensitivity in this study is one of the greatest on record.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
TUDCA stands for tauroursodeoxycholic acid. It is a bile acid that helps counteract other bile acids that become toxic. Supplementation with TUDCA has a diverse array of therapeutic potential.
- Reduces liver enzymes and liver stress by as much as 50%.
- Reduces cholesterol absorption.
- Enhances sensitivity to insulin.
- May be neuroprotective.
- Has potential to facilitate fat oxidation at higher doses.
Q: What is the best way to use TUDCA?
A: As a dietary supplement, take 1 serving once per day with a meal.
Q: Should I use TUDCA to treat my liver problem?
A: TUDCA is a dietary supplement, and therefore, it is not intended to treat, diagnose, cure, or prevent any disease.
Q: Can TUDCA be paired with any other MuscleSport products?
A: Yes. TUDCA can be used alongside any other MuscleSport products. It pairs nicely with LifeShield for optimal total health support.
- Invernizzi, P., Setchell, K. D., Crosignani, A., Battezzati, P. M., Larghi, A., O'Connell, N. C., & Podda, M. (1999). Differences in the metabolism and disposition of ursodeoxycholic acid and of its taurine‐conjugated species in patients with primary biliary cirrhosis. Hepatology, 29(2), 320-327.
- Crosignani, A., Budillon, G., Cimino, L., Del, C. V. B., Loguercio, C., Ideo, G., ... & Podda, M. (1998). Tauroursodeoxycholic acid for the treatment of HCV-related chronic hepatitis: a multicenter placebo-controlled study. Hepato-gastroenterology, 45(23), 1624-1629.
- Crosignani, A., Battezzati, P. M., Setchell, K. D., Invernizzi, P., Covini, G., Zuin, M., & Podda, M. (1996). Tauroursodeoxycholic acid for treatment of primary biliary cirrhosis. Digestive diseases and sciences, 41(4), 809-815.
- Kars, M., Yang, L., Gregor, M. F., Mohammed, B. S., Pietka, T. A., Finck, B. N., ... & Klein, S. (2010). Tauroursodeoxycholic acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women. Diabetes.
- Panella, C., Ierardi, E., De, M. M., Barone, M., Guglielmi, F. W., Polimeno, L., & Francavilla, A. (1995). Does tauroursodeoxycholic acid (TUDCA) treatment increase hepatocyte proliferation in patients with chronic liver disease?. The Italian journal of gastroenterology, 27(5), 256-258.
- Keene, C. D., Rodrigues, C. M., Eich, T., Chhabra, M. S., Steer, C. J., & Low, W. C. (2002). Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease. Proceedings of the National Academy of Sciences, 99(16), 10671-10676.
- Hardison, W. G., & Grundy, S. M. (1984). Effect of ursodeoxycholate and its taurine conjugate on bile acid synthesis and cholesterol absorption. Gastroenterology, 87(1), 130-135.
California’s Proposition 65 entitles California consumers to special warnings.
WARNING: Cancer and Reproductive Harm - www.P65warnings.ca.gov/